Agnello (Italian: [aɲˈɲɛllo]) is an Italian surname literally meaning "lamb". Notable people with the surname include:
- Bruno Agnello (born 1985), Brazilian football (soccer) midfielder
- Carmine Agnello (born 1960), New York mobster
- Carmine Gotti Agnello (born 1986)
- Chris Agnello (born 1968), American soccer coach
- Frank Gotti Agnello (born 1990)
- Giovanni Battista Agnello, author and alchemist
- John Gotti Agnello (born 1987)
- Louis "Cousin Vinny" Agnello
- Vincenzo Agnello Suardi (1582–1644), Roman Catholic prelate who served as Bishop of Mantua and Alba
See also
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