Doc or, less commonly, The Doc is the nickname of:
American Old West
- Doc Holliday (1851–1887), American gunfighter, gambler and dentist
 - William Frank Carver (1851–1927), American sharpshooter and Wild West show producer
 - Doc Scurlock (1849–1929), American cowboy and gunfighter
 - David Swinson Maynard (1808-1873), American pioneer and businessman, founder of Seattle
 
Sports
- Doc Adams (1814–1899), American baseball player and executive
 - Doc Adkins (1872–1934), American baseball player
 - Doc Alexander (1897–1975), American NFL football player and coach
 - Doc Amole (1878–1912), American baseball player
 - Doc Ayers (1891–1968), American baseball player
 - Darrel Baldock (1938–2011), Australian rules football player and coach and politician nicknamed "The Doc"
 - Doc Baker (died c. early 1920s), African-American football player
 - Doc Bass (1898–1970), American baseball player
 - Doc Bennett (1891–1974), American baseball player and manager
 - Doc Blanchard (1924–2009), American football player and fighter pilot
 - Doc Casey (1870–1936), American Major League Baseball player and manager
 - Matthew Clarke (Australian footballer) (born 1973), retired
 - Doc Cook (baseball) (1886–1973), American Major League Baseball player
 - L. J. Cooke (1868–1943), American college men's basketball coach
 - Doc Crandall (1887–1951), American Major League Baseball player, the first used consistently as a relief pitcher
 - Donald Dann (1949–2005), Australian Paralympic athlete
 - Seán Doherty (Gaelic footballer) (born 1947), Irish former Gaelic football manager and player
 - Ed Dougherty (born 1947), American golfer
 - Doc Edwards (1936–2018), American Major League Baseball player
 - Mike Emrick (born 1946), American hockey broadcaster
 - Julius Erving (born 1950), American basketball player
 - Doc Gautreau (1901–1970), American Major League Baseball player and manager
 - Doc Gessler (1880–1924), American Major League Baseball player
 - Dwight Gooden (born 1964), American Major League Baseball pitcher
 - Doctor Greenwood (1860–1951), English footballer
 - Roy Halladay (1977–2017), American Major League Baseball pitcher
 - Dick Hoblitzell (1888–1962), American Major League Baseball player
 - Arthur Irwin (1858–1921), Canadian-American Major League Baseball player and manager
 - Jack Kearns (1882–1963), American boxing manager, most notably for Jack Dempsey
 - Allan Kwartler (1917–1998), American sabre and foil fencer, Pan American Games and Maccabiah Games champion
 - Doc Lawson (born 1958), American soccer player
 - Doc MacKenzie (1906–1936), American race car driver
 - Doc McJames (1874–1901), American baseball player and physician
 - Walter Meanwell (1884–1953), college men's basketball coach
 - Doc Medich (born 1948), American baseball player
 - Cary Middlecoff (1921–1998), American golfer and dentist
 - Donald Minnegan (1902–2002), former coach and athletic director at Towson University
 - Gil Morgan (born 1946), American golfer
 - Harold Nicholls (1897–1977), New Zealand rugby football player
 - Danell Nicholson (born 1967), American former boxer
 - Donncha O'Callaghan (born 1979), Irish rugby union footballer
 - Derek Pace (1932–1989), English footballer
 - Doc Powers (1870–1909), American Major League Baseball player and physician
 - Doc Prothro (1893–1971), American Major League Baseball player and manager and dentist
 - Doc Redman (born 1997), American golfer
 - Ross Reynolds (1887–1970), American Major League Baseball pitcher
 - Doc Rivers (born 1961), American National Basketball Association player and coach
 - Johnny Rutherford (baseball) (1925–2016), Canadian former Major League Baseball pitcher
 - Harry Sage (1864–1947), American Major League Baseball player
 - Homer Smoot (1878–1928), American Major League Baseball player
 - Gary Wiggins (1952–2008), Australian cyclist nicknamed "The Doc"
 - Doc Wise (born 1967), American football player
 - George Yeager (1874–1940), American Major League Baseball player
 
Arts and entertainment
- Doc Bagby, American musician
 - Doc Brown (rapper) (born 1980), British rapper and comedian
 - Doc Cheatham (1905–1997), American jazz trumpeter, singer and bandleader
 - George Hager (1885–?), American illustrator and newspaper editorial cartoonist
 - Doc Hammer, American musician and writer of The Venture Bros
 - Owen Smith, Producer at game development company Uncommon Chocolate
 - Harold L. Humes (1926–1992), American writer and activist
 - Charles Kuhn (1892–1989), American cartoonist
 - Doc Neeson (1947–2014), Irish-born Australian rock singer
 - Doc Pomus (1925–1991), American blues singer and songwriter
 - David G. Robinson (theatre pioneer), 19th century theatrical pioneer in Northern California
 - Doc Searls (born 1947), American journalist, author and blogger
 - Doc Severinsen (born 1927), American trumpeter and bandleader
 - Doc Shaw (born 1992), American actor, singer and rapper
 - Neil Simon (1927–2018), American playwright and screenwriter
 - E. E. Smith (1890–1965), American science fiction writer
 - Doc Watson (1923-2012), American musician and songwriter
 
Military
- John Bahnsen (born 1934), retired US Army brigadier general
 - Donald E. Ballard (born 1945), American retired colonel and Medal of Honor recipient
 - John Bradley (United States Navy) (1923–1994), US Navy corpsman who participated in the raising of the flag on Iwo Jima
 - Donald M. Carpenter (1894–1940), early US Navy aviator
 - Ivan Dougherty (1907–1998), Australian Army major general
 - Ralph Eaton (1898–1986), US Army brigadier general
 - Robert H. Foglesong (born 1945), retired US Air Force general
 - Robert R. Ingram (born 1945), retired US Navy sailor and recipient of the Medal of Honor
 - Charles R. Jennison (1834–1888), American Civil War colonel and anti-slavery activist
 - Rick Jolly (1946–2018), former Royal Navy surgeon-captain nicknamed "The Doc"
 - Wheeler Bryson Lipes (1920–2005), US Navy pharmacist's mate who performed the first major surgery aboard a submarine
 - Harold Anthony Oaks (1896–1968), Canadian World War I flying ace
 - Lewis Powell (conspirator) (1844–1865), Confederate soldier hanged for his part in the Abraham Lincoln assassination plot
 - Alfred V. Rascon (born 1945), US Army retired lieutenant colonel and Medal of Honor recipient
 - William P. Sanders (1833–1863), Union Army officer during the American Civil War
 
Politicians and government officials
- A. A. Ames (1842–1911), American politician
 - David O. Cooke (1920–2002), American government administrator
 - Charles Edgar Edgett (1883–1947), Canadian police chief and anti-communist
 - H. V. Evatt (1894–1965), Australian politician
 - Doc Hastings (1941-), American politician
 - Robert Newell (politician) (1807–1869), American politician, fur trapper and frontier doctor
 - Dennis O'Keefe (politician), former mayor of St. John's, Newfoundland and Labrador, Canada
 
Other
- Arthur Barker (1899–1939), American criminal, son of Ma Barker and a member of the Barker-Karpis gang
 - John W. A. "Doc" Buyers (1928–2006), American business executive
 - Ruben Cavazos (born 1957), American criminal, former International President of the Mongols Motorcycle Club
 - Maurice Ewing (1906–1974), American geophysicist and oceanographer
 - Michael Keiner (born 1959), German poker player and plastic surgeon nicknamed "The Doc"
 - Doc Quigg (1911–1998), American journalist
 - Maynard Jack Ramsay (1914–2005), American entomologist
 - George M. Willing (1829–1874), American physician, prospector, and political lobbyist
 
See also
- All pages with titles beginning with Doc
 - All pages with titles containing Doc
 - Dock (given name)
 - François Duvalier (1907–1971), President of Haiti nicknamed "Papa Doc"
 - Jean-Claude Duvalier (1951–2014), President of Haiti nicknamed "Baby Doc", son of François Duvalier
 - Doctor (disambiguation)
 
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