HFS may refer to:
Computing
- Hierarchical file system, a system for organizing directories and files
 - Hierarchical File System (Apple), a file system introduced in 1985 for the classic Mac OS
 - Hierarchical File System (IBM MVS), a file system introduced in 1993 for MVS/ESA and subsequent operating systems
 - Hi Performance FileSystem, a file system used by the HP-UX operating system
 - HTTP File Server, a web server
 - Hardware functionality scan, a security mechanism used in Microsoft Windows operating systems
 
Education
- Haddonfield Friends School, in New Jersey, United States
 - Harford Friends School, in Maryland, United States
 - Hiranandani Foundation Schools, in India
 
Science and mathematics
Transportation
- French Frigate Shoals Airport, in Hawaii, United States
 - Hagfors Airport, in Sweden
 - Hatfield and Stainforth railway station, in England
 
Other uses
- Croatian Film Association (Croatian: Hrvatski filmski savez)
 - Hellenic Fire Service, in Greece
 - Hemifacial spasm, a neurologic disorder
 - High fructose syrup
 - Hospitality Franchise Systems, later Cendant
 - HFS Morgan, founder of Morgan Motor Company
 - WHFS (historic), a former radio station in the Washington, D.C./Baltimore, Maryland
 
See also
- High Performance File System, a file system for the OS/2 operating system
 
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