LOF may refer to:
In acronyms and codes:
- Lack-of-fit test (disambiguation), a concept in statistics
 - Libbey–Owens–Ford, an automotive and building glass manufacturer
 - Lloyd's Open Form: a type of salvage agreement offered by Lloyd's of London
 - Local Outlier Factor, an anomaly detection algorithm
 - Lok Fu station, Hong Kong (MTR station code)
 - London & Overseas Freighters, a defunct UK merchant shipping company
 - London Fields railway station, England (National Rail station code)
 - Trans States Airlines (ICAO designator)
 - Leftöver Crack, a NYC crust punk band
 
In other uses:
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