MECC is the Minnesota Educational Computing Consortium.
MECC may also refer to:
- MATRADE Exhibition and Convention Centre, in Kuala Lumpur, Malaysia
 - McKinley Exchange Corporate Center, an office building and bus terminal in Makati, Philippines
 - MECC Maastricht, Maastricht Exhibition & Conference Centre
 - Microbial electrolysis carbon capture
 - Middle East Cancer Consortium, an international initiative on cancer treatment and research
 - Middle East Council of Churches
 - Minimized extracorporeal circulation
 - Missouri Eastern Correctional Center, a male prison in central-eastern Missouri
 - Mountain Empire Community College, a community college located in Big Stone Gap, Virginia
 - Microsoft Excel Collegiate Challenge, an Microsoft Excel e-sport competition, first introduced in 2022
 
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