Mosi or MOSI may refer to:
- Mosi (given name)
 - Mosi (surname)
 - Molybdenum silicide (MoSi2), an important material in the semiconductor industry
 - MOSI protocol, an extension of the basic MSI cache coherency protocol
 - MOSI, Master Out Slave In (data output from master), Serial Peripheral Interface pin and logic signal
 - Museum of Science and Industry (MOSI), former name of the Science and Industry Museum in Manchester, England
 - Mosi (beer)
 
See also
- Museum of Science and Industry (disambiguation), several museums
 
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