MSX is a computer standard.
MSX may also refer to:
- MSX, a disease caused by the Haplosporidium nelsoni pathogen of oysters
 - Metal Slug X, a video game
 - Midcourse Space Experiment, an infrared satellite telescope
 - MSX, IATA code for Mossendjo Airport in the Republic of the Congo
 - Stanford MSx, a management program at Stanford University, formerly known as the Sloan Fellows Program
 
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