Look up SLE in Wiktionary, the free dictionary.
SLE may refer to:
Medicine
- Systemic lupus erythematosus, an autoimmune disease
 - St. Louis encephalitis, a mosquito-borne disease
 
Science and mathematics
- Semiconductor luminescence equations
 - Sea level equation, following post-glacial rebound
 - Schramm–Loewner evolution in statistical mechanics
 
Transportation
- McNary Field, airport in Salem, Oregon, US, IATA code
 - Seletar Expressway, Singapore
 - Sleeper Either Class, a type of railway car
 - Shore Line East commuter rail service in Connecticut, USA
 
Other
- Sara Lee Corporation, NYSE symbol
 - Separate legal entity in US
 - Single loss expectancy for risk on an asset
 - Societas Linguistica Europaea, a linguistics society
 - Sri Lankan English
 - Sierra Leone, ISO-3166-1 alpha-3 country code
 - Sierra Leonean leone currency code
 - Spearhead Land Element of UK armed forces
 - Supported leading edge kite, a type of power kite
 - SuSE SLE operating system
 - Sensory Logical Extrovert in socionics
 - The Space Link Extension of CCSDS
 
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