Sego may refer to:
- UR-100, a Soviet ICBM
 - Ségo, a nickname in the French press for French politician and 2007 Socialist presidential candidate Ségolène Royal
 - Sego lily, a plant native to the western United States
 - Sego (diet drink), a discontinued diet drink introduced by Pet Milk in 1961
 - Sego, Ohio, an unincorporated community
 - Sego, Utah, a ghost town in the United States
 
See also
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