Senju is a Japanese surname.
People with the surname include:
- Akira Senju (born 1960), a Japanese composer, arranger and conductor
 - Hiroshi Senju (born 1958), a Japanese painter
 - Miyazono Senju IV (1899–1985), a Japanese singer and shamisen player
 
Fictional characters
- Hashirama Senju, a character in the manga and anime series Naruto
 - Tobirama Senju, a character from the manga and anime series Naruto
 - Tsunade Senju, a character from the manga and anime series Naruto
 
See also
- Kita-Senju Station, in Tokyo
 - Minami-Senju Station, in Tokyo
 - Senju-ji, a Buddhist temple
 - Senju Thermal Power Station, in Tokyo
 
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