XFS is a computer file system created by Silicon Graphics.
XFS may also refer to:
- X Font Server, a standard mechanism for an X server to communicate with a font renderer
 - CEN/XFS, a client-server architecture for financial applications on the Microsoft Windows platform
 - Exfoliation syndrome, an eye ailment
 
See also
- Extent File System (EFS), a file system superseded by XFS
 - CXFS (Clustered XFS), a shared disk file system designed by Silicon Graphics
 
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