| Tournament details | |
|---|---|
| Country | .svg.png.webp) Northern Ireland  Republic of Ireland | 
| Teams | 8 | 
| Defending champions | Linfield | 
| Final positions | |
| Champions | Drogheda United (1st title) | 
| Runner-up | Cork City | 
| Tournament statistics | |
| Matches played | 27 | 
| Goals scored | 59 (2.19 per match) | 
The 2006 Setanta Sports Cup was the 2nd staging of the Setanta Sports Cup, a cross-border cup competition that takes place between football clubs from the Republic of Ireland and Northern Ireland. The final was played at Tolka Park in Dublin, Republic of Ireland on 22 April 2006, where Drogheda United beat Cork City to win the competition for the first time.
Group stage
The draw for this round was held 12 December 2005. The matches were played 20 February 2006 – 3 April 2006.
Group A
| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts | Qualification | 
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  Cork City (A) | 6 | 5 | 1 | 0 | 11 | 2 | +9 | 16 | Advanced to the semi-finals | 
| 2 |  Drogheda Utd (A) | 6 | 3 | 1 | 2 | 7 | 5 | +2 | 10 | |
| 3 | .svg.png.webp) Dungannon Swifts | 6 | 1 | 1 | 4 | 4 | 8 | −4 | 4 | |
| 4 | .svg.png.webp) Portadown | 6 | 0 | 3 | 3 | 4 | 11 | −7 | 3 | 
(A) Advance to a further round
| Cork City | 2 – 0 | Drogheda United | 
|---|---|---|
| Behan  58' Gavin o.g.  80' | (Report) | Bradley  76' Fahey  77' | 
 Alan Kelly
 Alan Kelly| Dungannon Swifts | 1 – 1 | Portadown | 
|---|---|---|
| McAree  85 pen' | (Report) | Convery  23' | 
| Cork City | 2 – 0 | Dungannon Swifts | 
|---|---|---|
| O'Flynn  39' O'Callaghan  47' O'Donovan  28' | (Report) | 
| Drogheda United | 4 – 0 | Portadown | 
|---|---|---|
| Keegan  7' Barrett  9' O'Brien  33',  55' | (Report) | Neill  69' | 
| Dungannon Swifts | 1 – 2 | Drogheda United | 
|---|---|---|
| Scullion  74' | (Report) | O'Brien  9' Bradley  59' | 
| Drogheda United | 0 – 2 | Cork City | 
|---|---|---|
| Connor  78' | (Report) | Behan  13' O'Callaghan  79 pen' | 
| Portadown | 1 – 2 | Dungannon Swifts | 
|---|---|---|
| McStay  86' | (Report) | Adamson  74' Bulow  84' | 
Group B
| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts | Qualification | 
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | .svg.png.webp) Linfield (A) | 6 | 2 | 4 | 0 | 12 | 4 | +8 | 10 | Advanced to the semi-finals | 
| 2 |  Shelbourne (A) | 6 | 2 | 3 | 1 | 7 | 3 | +4 | 9 | |
| 3 |  Derry City | 6 | 1 | 4 | 1 | 5 | 4 | +1 | 7 | |
| 4 | .svg.png.webp) Glentoran | 6 | 1 | 1 | 4 | 5 | 18 | −13 | 4 | 
(A) Advance to a further round
| Linfield | 1 – 1 | Derry City | 
|---|---|---|
| Thompson  9' | (Report) | Farren  16' | 
| Shelbourne | 3 – 0 | Glentoran | 
|---|---|---|
| Ryan  29' Crowe  36',  60' | (Report) | 
| Glentoran | 3 – 3 | Linfield | 
|---|---|---|
| Lockhart  11' Nixon  21 pen' Browne  74' | (Report) | McAreavey  17' Kearney  50',  69' Ferguson  57' | 
| Derry City | 3 – 1 | Glentoran | 
|---|---|---|
| Hargan  11',  35' Beckett  38' | (Report) | Walker  90' | 
| Linfield | 2 – 0 | Shelbourne | 
|---|---|---|
| Gault  35' Thompson  53' | (Report) | 
| Shelbourne | 0 – 0 | Linfield | 
|---|---|---|
| Hawkins  75' | (Report) | McAreavey  24' | 
 Alan Kelly
 Alan Kelly| Shelbourne | 1 – 1 | Derry City | 
|---|---|---|
| Byrne  17' | (Report) | Martyn  89' | 
Semi-finals
The draw for the semi-finals was made by drawing the winners of Group A against the runners-up of Group B and vice versa, with group winners having home advantage. There would be no replays if the matches were drawn; instead, extra time would decide winners immediately thereafter. If extra time did not decide the winners, a set of five alternating penalty kicks would decide winners.
| Cork City | 2 – 0 | Shelbourne | 
|---|---|---|
| O'Brien  34' Fenn  62' | (Report) | 
| Linfield | 0 – 1 | Drogheda United | 
|---|---|---|
| (Report) | Keddy  33' | 
Final
Similarly to the semi-finals, there would be no replay even if the match was drawn; instead, extra time would be used to decide the winners. If extra time failed to separate the two sides, the match would go to penalties.
| Cork City | 0 – 1 (AET) | Drogheda United | 
|---|---|---|
| (Report) | Leech  102' | 
| Winner of 2006 Setanta Sports Cup | 
|---|
|  Drogheda United 1st title | 
Goalscorers
- 4 goals
 Denis Behan (Cork City) Denis Behan (Cork City)
.svg.png.webp) Peter Thompson (Linfield) Peter Thompson (Linfield)
- 3 goals
 Jason Byrne (Shelbourne) Jason Byrne (Shelbourne)
 George O'Callaghan (Cork City) George O'Callaghan (Cork City)
.svg.png.webp) Paul McAreavey (Linfield) Paul McAreavey (Linfield)
 Declan O'Brien (Drogheda United) Declan O'Brien (Drogheda United)
- 2 goals
 Glen Crowe (Shelbourne) Glen Crowe (Shelbourne)
.svg.png.webp) Sean Hargan (Derry City) Sean Hargan (Derry City)
.svg.png.webp) Oran Kearney (Linfield) Oran Kearney (Linfield)
 Mark Leech (Drogheda United) Mark Leech (Drogheda United)
 John O'Flynn (Cork City) John O'Flynn (Cork City)
- 1 goal
.svg.png.webp) Timmy Adamson (Dungannon Swifts) Timmy Adamson (Dungannon Swifts)
 Shane Barrett (Drogheda United) Shane Barrett (Drogheda United)
 Gary Beckett (Derry City) Gary Beckett (Derry City)
 Stephen Bradley (Drogheda United) Stephen Bradley (Drogheda United)
.svg.png.webp) Gary Browne (Glentoran) Gary Browne (Glentoran)
 David Bulow (Dungannon Swifts) David Bulow (Dungannon Swifts)
 Ollie Cahill (Shelbourne) Ollie Cahill (Shelbourne)
.svg.png.webp) John Convery (Portadown) John Convery (Portadown)
 Mark Farren (Derry City) Mark Farren (Derry City)
 Neale Fenn (Cork City) Neale Fenn (Cork City)
.svg.png.webp) Michael Gault (Linfield) Michael Gault (Linfield)
.svg.png.webp) Andrew Hunter (Linfield) Andrew Hunter (Linfield)
 James Keddy (Drogheda United) James Keddy (Drogheda United)
 Paul Keegan (Drogheda United) Paul Keegan (Drogheda United)
.svg.png.webp) Darren Kelly (Portadown) Darren Kelly (Portadown)
.svg.png.webp) Darren Lockhart (Glentoran) Darren Lockhart (Glentoran)
 Ciarán Martyn (Derry City) Ciarán Martyn (Derry City)
.svg.png.webp) Rodney McAree (Dungannon Swifts) Rodney McAree (Dungannon Swifts)
.svg.png.webp) Henry McStay (Portadown) Henry McStay (Portadown)
.svg.png.webp) William Murphy (Linfield) William Murphy (Linfield)
.svg.png.webp) Colin Nixon (Glentoran) Colin Nixon (Glentoran)
 Colin O'Brien (Cork City) Colin O'Brien (Cork City)
.svg.png.webp) Paddy Quinn (Portadown) Paddy Quinn (Portadown)
 Jamie Reed (Glentoran) Jamie Reed (Glentoran)
 Bobby Ryan (Shelbourne) Bobby Ryan (Shelbourne)
.svg.png.webp) David Scullion (Dungannon Swifts) David Scullion (Dungannon Swifts)
.svg.png.webp) Chris Walker (Glentoran) Chris Walker (Glentoran)
 Billy Woods (Cork City) Billy Woods (Cork City)
- 1 own goal
 Jason Gavin (Drogheda United) Jason Gavin (Drogheda United)